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Symbol
Name
ID
Cfb
complement factor B
MGI:105975
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Purpura
Persistence of hemoglobin F
Increased mean corpuscular volume
Reticulocytosis
Hemolytic anemia
Chronic hemolytic anemia
Increased red cell sickling tendency
Hypochromic anemia
Iron deficiency anemia
Microcytic anemia
Target cells
Leukocytosis
Acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Thrombocytosis
Lymphoma
Abnormality of the spleen
Splenic infarction
Splenomegaly
Disease(s) Associated with CFB
acute lymphoblastic leukemia
IgA glomerulonephritis
sickle cell anemia

Mouse Phenotypes
increased erythrocyte cell number
increased hematocrit
increased hemoglobin content
Availability Mouse Genotype
Cfbtm1.1(KOMP)Wtsi/Cfbtm1.1(KOMP)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory